Crystallography Illuminates Drug Targets

James Netterwald, PhD, MT(ASCP), Senior Editor, Drug Discovery & Development

Knowing the structure of a protein used to be of greater importance to basic biological science than to applied biomedical science. However, as these fields converge, knowing and understanding protein structure has become imperative for both. X-ray crystallography, the most important tool for determining protein structure, is the preeminent tool of the relatively new science of structural biology, but its use in science in general is not new at all.

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